hide random home screenshot http://condor.bcm.tmc.edu/3DEM/3dem-home.html (World Wide Web Directory, 06/1995)

3DEM Home Page

Welcome To The 3DEM Resource Center


W.M. Keck Center for Computational Biology

Verna and Marrs McLean Department of Biochemistry
Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030

Director: Wah Chiu, Ph.D.


The 3DEM Resource Center at Baylor College of Medicine is a national facility for intermediate electron cryomicroscopy and image reconstruction supported by the NIH National Center of Research Resources. Our missions include technology development, collaborative and service research, training, and technology dissemination. A committee of expert scientists provides advice on the activities of the Center.

Our specialty is the development of the technology of electron imaging and the diffraction of biological macromolecular assembly towards atomic resolution. We have active research development underway in the following areas: use of a low temperature cryo-specimen holder, computer controlled data collection, data acquisition in a CCD camera, formation of highly ordered 2D arrays, reduction of specimen charging, and development of interactive software for 3D reconstruction. ICE (Interactive Crystallographic Environment), our integrated graphic software for processing images of 2D arrays, is available free of charge to interested researchers.

We are currently engaged in active collaborative projects involving cytoskeletal protein assembly, viruses, the protein-nucleic acid complex, and membrane channel proteins, which are difficult to study by X-ray crystallography and NMR. We invite applications from interested researchers desiring to use our facility. Applicants should fill out a one-page form and include a C.V. and project and funding summaries. If you have any questions, please contact:

* Director: Wah Chiu, Ph.D.

* Co-Director: Michael F. Schmid, Ph.D..

Fearless Leaders

Dr. Chiu and Dr. Schmid in front of the 3DEM Resource Center's JEOL 4000 Microscope

Our FAX number is 713-796-9438.


Online Resources of the 3DEM Resource Center:

* Description of Current Core Research Projects

  • Crotoxin
  • Herpes Simplex Virus
  • * Faculty, Fellows, Students, and Staff at the 3DEM Resource Center

    * Selected Recent Publications by Resource Center Researchers

    * Annual 3DEM Center Workshop

    * Information for Researchers Interested in Using the Center's Facilities

    * Opportunites for Undergraduate, Postgraduate, and Postdoctoral Research



    Baylor College of Medicine Home Page BCM
    HyperText by Bin Wang, and Chris Scanlan.
    Technical assistance by Jaap Brink is acknowledged.
    For question or comments, send e-mail to zwang@bcm.tmc.edu or cscanlan@bcm.tmc.edu.
    Last update 1/27/95